Smooth away laugh lines with natural-looking results. Restylane Refyne is a hyaluronic acid-based filler designed to soften nasolabial folds and marionette lines while preserving your natural facial movement and expression.
If you’re seeking a non-surgical solution to facial aging, Restylane® Refyne may be the ideal choice for you.
What Is Restylane® Refyne?
Restylane Refyne is a next-generation dermal filler formulated with XpresHAn Technology™, allowing for smooth, flexible results that move naturally with your facial expressions. This FDA-approved injectable is specifically designed to treat moderate to severe lines around the mouth and nose, such as:
- Nasolabial folds (smile lines)
- Marionette lines (lines from the corners of the mouth to the chin)
Unlike thicker fillers, Refyne is soft and flexible, making it ideal for dynamic areas of the face where expressions are frequent. At Cultura Dermatology & Plastic Surgery, we use Restylane® Refyne to restore volume, soften wrinkles, and help you maintain a refreshed yet natural look.

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Long-Lasting Results
Restylane® Refyne provides natural and smooth results that can last for up to 12 months, offering you a rejuvenated appearance that stands the test of time.
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Quick Treatment
The procedure is swift and can typically be completed within 15 to 30 minutes, making it convenient for those with busy schedules.
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Minimal Discomfort
Restylane® Refyne treatments involve minimal discomfort, and topical numbing can be applied to enhance your comfort during the procedure.
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Proven Safety
Restylane® Refyne has undergone rigorous testing to ensure both its effectiveness and safety, with mild and short-lived side effects reported in clinical studies.
Who Is a Good Candidate?
Restylane Refyne is ideal for individuals who:
- Want to smooth moderate to severe laugh lines without surgery
- Are seeking natural-looking enhancement that moves with facial expressions
- Are in good general health and have no allergies to hyaluronic acid or lidocaine
- Prefer subtle, soft results over more dramatic volume
Your Cultura provider will perform a thorough consultation to determine if Restylane Refyne is the best fit for your goals.
What Does Restylane® Treat?
Aesthetic Concerns |
Restylane helps restore lost facial volume, smooth wrinkles, and rejuvenate the skin, giving you a refreshed, youthful appearance. |
Functional Concerns |
As skin ages or loses volume, it can affect facial structure and comfort. Restylane restores volume and enhances skin elasticity, improving both form and function. |
Medical Concerns |
Restylane is a safe, minimally invasive dermal filler that can treat volume loss in the face, reduce wrinkles, and provide natural-looking results with minimal downtime. |
What to Expect During Treatment
After your consultation, your provider will cleanse the treatment area and apply a topical anesthetic if needed. Refyne is injected using a fine needle, and most treatments take under 30 minutes. The filler includes lidocaine for added comfort.
Mild swelling, redness, or bruising may occur but typically resolves within a few days. Many patients return to daily activities immediately.
- How long does Restylane Refyne last?
- Is the procedure painful?
- Can Restylane Refyne be combined with other treatments?
- How is Refyne different from other Restylane fillers?
- When will I see results?
Why Choose Cultura for Your Restylane® Refyne Session
At Cultura, your injectable experience is guided by precision, artistry, and a deep understanding of how the face moves and ages. Our team specializes in treatments that restore your natural beauty without sacrificing expression or individuality. With Restylane Refyne, we focus on enhancing your look in the most subtle, seamless way.
Our providers are trained in the latest filler techniques and tailor every treatment plan to your unique anatomy, goals, and skin tone. Whether you’re new to fillers or refining previous work, Cultura offers an elevated standard of care in a welcoming, inclusive environment.
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20+
YEARS OF EXPERIENCE
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100000+
LASER HAIR REMOVAL TREATMENTS
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32+
CULTURALLY AWARE DOCTORS

Book Your Consultation Today
Revitalize your skin’s texture and restore youthful volume. Schedule your Restylane® consultation today and explore a customized treatment plan designed around your unique features, goals, and lifestyle.
Dr. Eliot Battle
Dr. Eliot Battle, CEO of Cultura Dermatology, is a global leader in cosmetic dermatology and laser innovation. His Harvard research pioneered “color-blind” lasers, making treatments safe for all skin tones. A sought-after expert featured in TIME, Oprah, and The New York Times, he continues to advance inclusive, cutting-edge dermatological care.